Bone Marrow or Peripheral Blood

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ALL at Initial Diagnosis Peripheral blood Bone marrow Surface Stirface

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Infections after Transplantation of Bone Marrow or Peripheral Blood Stem Cells from Unrelated Donors.

Infection is a major complication of hematopoietic cell transplantation. Prolonged neutropenia and graft-versus-host disease are the 2 major complications with an associated risk for infection, and these complications differ according to the graft source. A phase 3, multicenter, randomized trial (Blood and Marrow Transplant Clinical Trials Network [BMT CTN] 0201) of transplantation of bone marr...

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Quality of life in patients randomized to receive a bone marrow or a peripheral blood allograft.

BACKGROUND AND OBJECTIVES Quality of life (QOL) is an important clinical end-point to be considered in the late follow-up of patients treated with allogeneic bone marrow (BM) or peripheral blood progenitor cell (PBPC) transplantation. DESIGN AND METHODS To assess the QOL in a group of survivors of hematologic malignancies who had been enrolled in a prospective randomized trial comparing allog...

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Prostaglandins of the E series (PGE) inhibit proliferation of normal bone marrow granulocyte/macrophage progenitors (CFU-GM). Circulating CFU-GM are known to differ from marrow CFU-GM in many characteristics, and in the present study, we compared the effect of PGE1 on circulating and bone marrow progenitors in normals and in patients with chronic myelogenous leukemia (CML). PGE, caused a dose-d...

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Peripheral-blood stem cells versus bone marrow from unrelated donors.

BACKGROUND Randomized trials have shown that the transplantation of filgrastim-mobilized peripheral-blood stem cells from HLA-identical siblings accelerates engraftment but increases the risks of acute and chronic graft-versus-host disease (GVHD), as compared with the transplantation of bone marrow. Some studies have also shown that peripheral-blood stem cells are associated with a decreased ra...

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ژورنال

عنوان ژورنال: Biology of Blood and Marrow Transplantation

سال: 2010

ISSN: 1083-8791

DOI: 10.1016/j.bbmt.2008.05.015